Article
Silver nanoparticle-based ultrasensitive chemiluminescent detection of DNA hybridization and single-nucleotide polymorphisms.
Analytical chemistry - 1 Jun 2006
Liu Cheng-Hui, Li Zheng-Ping, Du Bao-An, Duan Xin-Rui, Wang Yu-Cong
Abstract excerpt
A new nanoparticle-based chemiluminescent (CL) method has been developed for the ultrasensitive detection of DNA hybridization. The assay relies on a sandwich-type DNA hybridization in which the DNA targets are first hybridized to the captured oligonucleotide probes immobilized on polystyrene mic...
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