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Article

Protein phosphatase 1 is a molecular constraint on learning and memory.

Nature - 29 Aug 2002

Genoux David, Haditsch Ursula, Knobloch Marlen, Michalon Aubin, Storm Daniel, Mansuy Isabelle M

Abstract excerpt

Repetition in learning is a prerequisite for the formation of accurate and long-lasting memory. Practice is most effective when widely distributed over time, rather than when closely spaced or massed. But even after efficient learning, most memories dissipate with time unless frequently used. The molecular mechanisms of these time-dependent constraints on learning and memory are unknown. Here we show that protein...

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Source

Identifiers

PMID: 12198546
DOI: 10.1038/nature00928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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