Article
Age-acquired immunity to a Plasmodium vivax invasion ligand, the duffy binding protein.
The Journal of infectious diseases - 15 Aug 2002
Cole-Tobian Jennifer L, Cortés Alfred, Baisor Moses, Kastens Will, Xainli Jia, Bockarie Moses, Adams John H, King Christopher L
Abstract excerpt
The interaction between the Plasmodium vivax merozoite Duffy binding protein region II (DBPII) and the human erythrocyte Duffy antigen leads to infection. Highly polymorphic regions of this protein may have arisen as a mechanism to avoid host immunity. To examine whether immunity to P. vivax is d...
Topics
- Adult
- Aging
- Alleles
- Amino Acid Sequence
- Animals
- Antibodies, Protozoan
- Antigens, Protozoan
- Base Sequence
- Carrier Proteins
- Child
- Child, Preschool
- Duffy Blood-Group System
- Gene Frequency
- Haplotypes
- Humans
- Ligands
- Malaria, Vivax
- Middle Aged