Article
Duffy antigen receptor for chemokine (DARC) polymorphisms and its involvement in acquisition of inhibitory anti-duffy binding protein II (DBPII) immunity.
PloS one - 1 Jan 2014
Souza-Silva Flávia A, Torres Letícia M, Santos-Alves Jessica R, Tang Michaelis Loren, Sanchez Bruno A M, Sousa Tais N, Fontes Cor J F, Nogueira Paulo A, Rocha Roberto S, Brito Cristiana F A, Adams John H, Kano Flora S, Carvalho Luzia H
Abstract excerpt
The Plasmodium vivax Duffy binding protein (PvDBP) and its erythrocytic receptor, the Duffy antigen receptor for chemokines (DARC), are involved in the major P. vivax erythrocyte invasion pathway. An open cohort study to analyze DARC genotypes and their relationship to PvDBP immune responses was...
Topics
- Adolescent
- Adult
- Alleles
- Antigens, Protozoan
- Cross-Sectional Studies
- Duffy Blood-Group System
- Follow-Up Studies
- Gene Frequency
- Genotype
- Humans
- Malaria, Vivax
- Male
- Middle Aged
- Polymorphism, Genetic