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Article

Stimulation of 3'-->5' exonuclease and 3'-phosphodiesterase activities of yeast apn2 by proliferating cell nuclear antigen.

Molecular and cellular biology - 1 Sept 2002

Unk Ildiko, Haracska Lajos, Gomes Xavier V, Burgers Peter M J, Prakash Louise, Prakash Satya

Abstract excerpt

The Apn2 protein of Saccharomyces cerevisiae contains 3'-->5' exonuclease and 3'-phosphodiesterase activities, and these activities function in the repair of DNA strand breaks that have 3'-damaged termini and which are formed in DNA by the action of oxygen-free radicals. Apn2 also has an AP endonuclease activity and functions in the removal of abasic sites from DNA. Here, we provide evidence for the physical and...

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Identifiers

PMID: 12192046
DOI: 10.1128/MCB.22.18.6480-6486.2002
PMCID: PMC135640

Genes

PCNA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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