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Article

Physical and functional interaction of human nuclear uracil-DNA glycosylase with proliferating cell nuclear antigen.

DNA repair - 8 Dec 2005

Ko Rinkei, Bennett Samuel E

Abstract excerpt

Uracil residues arise in DNA by the misincorporation of dUMP in place of dTMP during DNA replication or by the deamination of cytosine in DNA. Uracil-DNA glycosylase initiates DNA base excision repair of uracil residues by catalyzing the hydrolysis of the N-glycosylic bond linking the uracil base to deoxyribose. In human cells, the nuclear form of uracil-DNA glycosylase (UNG2) contains a conserved PCNA-binding...

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Identifiers

PMID: 16216562
DOI: 10.1016/j.dnarep.2005.08.006
PMCID: PMC3040124

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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