Article
Gender-dependent effect of GSTM1 genotype on childhood asthma associated with prenatal tobacco smoke exposure.
BioMed research international - 1 Jan 2014
Wu Chih-Chiang, Ou Chia-Yu, Chang Jen-Chieh, Hsu Te-Yao, Kuo Ho-Chang, Liu Chieh-An, Wang Chih-Lu, Chuang Chia-Ju, Chuang Hau, Liang Hsiu-Mei, Yang Kuender D
Abstract excerpt
It remains unclear whether the GSTM1 genotype interacts with tobacco smoke exposure (TSE) in asthma development. This study aimed to investigate the interactions among GSTM1 genotype, gender, and prenatal TSE with regard to childhood asthma development. In a longitudinal birth cohort in Taiwan, 756 newborns completed a 6-year follow-up, and 591 children with DNA samples available for GSTM1 genotyping were...
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