Article
Association of CTLA-4 variation with type I diabetes in Filipinos.
Immunogenetics - 1 Aug 2002
Klitz William, Bugawan Teodorica L, Panelo Araceli, Solfelix Cecilia M, Buzzetti Raffaella, Pozzilli Paolo, Steiner Lori, Alejandrino Maria, Erlich Henry A
Abstract excerpt
The role of non-HLA single nucleotide polymorphisms from a panel of candidate genes in genetic susceptibility to type I diabetes (TID) among Filipinos was examined by PCR/SSOP typing of 90 patients and 94 controls, previously typed for the HLA class I and class II loci. We report the association of CTLA-4 A49G variation (cytotoxic T-lymphocyte associated-4) to TID among Filipinos, consistent with some but not all...
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