Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

T594M mutation of the beta-subunit of the epithelial sodium channel in Ghanaian populations from Kumasi and London and a possible association with hypertension.

Genetic testing - 1 Jan 2002

Dong Y B, Plange-Rhule J, Owusu I, Micah F, Eastwood J B, Carter N D, Saggar-Malik A K, Cappuccio F P, Jeffery S

Abstract excerpt

We have tested 186 individuals from Ghana, 95 indigenous and 91 who have settled in the United Kingdom, for the presence of the T594M mutation in the beta-subunit of the epithelial sodium channel, which is associated with hypertension in black populations. The group living in Ghana had a mean age of 27 years and were normotensive, but had an increased frequency of the T allele compared to the London-based...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Black People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelium

Share to Hypertension

Share to London

Share to Mutation, Missense

Share to Sodium Channels

Source

Identifiers

PMID: 12180079
DOI: 10.1089/109065702760093942

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

T594M mutation of the beta-subunit of the epithelial sodium channel in Ghanaian populations from Kumasi and London and a possible association with hypertension.PMID 12180079Read ↗

T594M variant of the epithelial sodium channel beta-subunit gene and hypertension in individuals of African ancestry in South Africa.Semantic proximity Read ↗

CLCNKB-T481S and essential hypertension in a Ghanaian population.Semantic proximity Read ↗

T594M mutation of the epithelial sodium channel beta-subunit gene in pre-eclampsia and eclampsia in Black South African women.Semantic proximity Read ↗

Association of pre-eclampsia with the R563Q mutation of the beta-subunit of the epithelial sodium channel.Semantic proximity Read ↗

Screening for GJB2-R143W-Associated Hearing Impairment: Implications for Health Policy and Practice in Ghana.Semantic proximity Read ↗

The R563Q mutation of the epithelial sodium channel beta-subunit is associated with hypertension.Semantic proximity Read ↗

Genetic variation in the epithelial sodium channel: a risk factor for hypertension in people of African origin.Semantic proximity Read ↗

A novel variant of the beta-subunit of the amiloride-sensitive sodium channel in African Americans.Semantic proximity Read ↗

Lack of association of 3 functional gene variants with hypertension in African Americans.Semantic proximity Read ↗

β-T594M epithelial sodium channel gene polymorphism and essential hypertension in individuals of Indo-Aryan ancestry in Northern India.Semantic proximity Read ↗

The association of the R563Q genotype of the ENaC with phenotypic variation in Southern Africa.Semantic proximity Read ↗

T594M mutation in the ENaC beta subunit and low-renin hypertension in blacks.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.