Article
β-T594M epithelial sodium channel gene polymorphism and essential hypertension in individuals of Indo-Aryan ancestry in Northern India.
Indian heart journal - 1 Jan 2000
Gupta Mohit D, Girish M P, Sikdar Sunandan, Ahuja Ramandeep, Shah Dhaval, Kumar Rahul, Rain Manjari, Nejatizadeh Azim, Tyagi Sanjay, Pasha Qadar
Abstract excerpt
BACKGROUND: The T594M variant of the β-subunit of the sodium epithelial channel (ENaC) gene may contribute to hypertension in individuals of Indo-Aryan origin. METHODS: Present study was performed to assess the role of the ENaC gene variant as an independent risk factor for hypertension in subjects of Indo-Aryan ancestry. A total of 150 patients of recently detected essential hypertension and 150 matched controls...
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