Article
T594M variant of the epithelial sodium channel beta-subunit gene and hypertension in individuals of African ancestry in South Africa.
American journal of hypertension - 1 Oct 2003
Nkeh Benedicta, Samani Nilesh J, Badenhorst Danelle, Libhaber Elena, Sareli Pinhas, Norton Gavin R, Woodiwiss Angela J
Abstract excerpt
BACKGROUND: The T594M variant of the beta-subunit of the sodium epithelial channel (ENaC) gene may contribute to hypertension in individuals of African origin. METHODS: A case-control study was performed to assess the role of the ENaC gene variant as an independent risk factor for hypertension in subjects of African ancestry. The effects of the ENaC gene variant on ambulatory blood pressure (BP) in hypertensive...
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