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Article

Screening for GJB2-R143W-Associated Hearing Impairment: Implications for Health Policy and Practice in Ghana.

Public health genomics - 1 Jan 2020

Adadey Samuel M, Quaye Osbourne, Amedofu Geoffrey K, Awandare Gordon A, Wonkam Ambroise

Abstract excerpt

Genetic factors significantly contribute to the burden of hearing impairment (HI) in Ghana as there is a high carrier frequency (1.5%) of the connexin 26 gene founder variant GJB2-R143W in the healthy Ghanaian population. GJB2-R143W mutation accounts for nearly 26% of causes in families segregating congenital non-syndromic HI. With HI associated with high genetic fitness, this indicates that Ghana will likely...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33302283
DOI: 10.1159/000512121

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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