Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in the epithelial sodium channel: a risk factor for hypertension in people of African origin.

Advances in renal replacement therapy - 1 Jan 2004

Swift Pauline A, Macgregor Graham A

Abstract excerpt

High blood pressure occurs commonly in individuals of African origin, leading to an increased risk of cardiovascular and end-stage renal disease (ESRD). Black individuals frequently have low plasma renin activity, and their blood pressure responds well to salt reduction, suggesting that abnormalities in renal sodium handling may be important in the etiology of hypertension in this population. The epithelial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amiloride
Share to Black People
Share to Diuretics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epithelial Sodium Channels

Share to London

Share to Methionine

Share to Sodium Channels

Share to Threonine

Source

Identifiers

PMID: 14730541
DOI: 10.1053/j.arrt.2003.10.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in the epithelial sodium channel: a risk factor for hypertension in people of African origin.PMID 14730541Read ↗

T594M variant of the epithelial sodium channel beta-subunit gene and hypertension in individuals of African ancestry in South Africa.Semantic proximity Read ↗

The association of the R563Q genotype of the ENaC with phenotypic variation in Southern Africa.Semantic proximity Read ↗

The renal epithelial sodium channel: genetic heterogeneity and implications for the treatment of high blood pressure.Semantic proximity Read ↗

Association of pre-eclampsia with the R563Q mutation of the beta-subunit of the epithelial sodium channel.Semantic proximity Read ↗

The R563Q mutation of the epithelial sodium channel beta-subunit is associated with hypertension.Semantic proximity Read ↗

β-T594M epithelial sodium channel gene polymorphism and essential hypertension in individuals of Indo-Aryan ancestry in Northern India.Semantic proximity Read ↗

A novel variant of the beta-subunit of the amiloride-sensitive sodium channel in African Americans.Semantic proximity Read ↗

Genetic forms of human hypertension.Semantic proximity Read ↗

Genetic epidemiology of hypertension: an update on the African diaspora.Semantic proximity Read ↗

Blood pressure regulation via the epithelial sodium channel: From gene to kidney and beyondSemantic proximity Read ↗

Genetic factors contributing to hypertension in African-based populations: A systematic review and meta-analysis.Semantic proximity Read ↗

The importance of G protein-coupled receptor kinase 4 (GRK4) in pathogenesis of salt sensitivity, salt sensitive hypertension and response to antihypertensive treatment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.