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White Cells Facilitate Opposite- and Same-Sex Mating of Opaque Cells in Candida albicans

16 Oct 2014

Abstract excerpt

Modes of sexual reproduction in eukaryotic organisms are extremely diverse. The human fungal pathogen Candida albicans undergoes a phenotypic switch from the white to the opaque phase in order to become mating-competent. In this study, we report that functionally- and morphologically-differentiated white and opaque cells show a coordinated behavior during mating. Although white cells are mating-incompetent, they...

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PMID: 25329547
DOI: 10.1371/journal.pgen.1004737

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