Article
Microscopic kinetics and structure-function analysis in the vesicular acetylcholine transporter.
Neurochemistry international - 1 Nov 2002
Bravo Dawn, Parsons Stanley M
Abstract excerpt
The vesicular acetylcholine transporter (VAChT) resides in synaptic vesicles of cholinergic nerve terminals. It carries out vesicular storage of ACh. The amount of ACh stored determines, along with other factors, the amount of ACh released. Knowledge of the structure-function relationship in VAChT might enable pharmacological regulation of ACh storage and release at the level of VAChT. To this end, a quantitative...
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