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Article

Desensitization contributes to the synaptic response of gain-of-function mutants of the muscle nicotinic receptor.

The Journal of general physiology - 1 Nov 2006

Elenes Sergio, Ni Ying, Cymes Gisela D, Grosman Claudio

Abstract excerpt

Although the muscle nicotinic receptor (AChR) desensitizes almost completely in the steady presence of high concentrations of acetylcholine (ACh), it is well established that AChRs do not accumulate in desensitized states under normal physiological conditions of neurotransmitter release and clear...

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Identifiers

PMID: 17074980
DOI: 10.1085/jgp.200609570
PMCID: PMC2151585

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17074980-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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