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Article

Stoichiometry for activation of neuronal α7 nicotinic receptors.

Proceedings of the National Academy of Sciences of the United States of America - 17 Dec 2013

Andersen Natalia, Corradi Jeremías, Sine Steven M, Bouzat Cecilia

Abstract excerpt

Neuronal α7 nicotinic receptors elicit rapid cation influx in response to acetylcholine (ACh) or its hydrolysis product choline. They contribute to cognition, synaptic plasticity, and neuroprotection and have been implicated in neurodegenerative and neuropsychiatric disorders. α7, however, often localizes distal to sites of nerve-released ACh and binds ACh with low affinity, and thus elicits its biological...

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Identifiers

PMID: 24297903
DOI: 10.1073/pnas.1315775110
PMCID: PMC3870720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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