Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

End-plate acetylcholine receptor: structure, mechanism, pharmacology, and disease.

Physiological reviews - 1 Jul 2012

Sine Steven M

Abstract excerpt

The synapse is a localized neurohumoral contact between a neuron and an effector cell and may be considered the quantum of fast intercellular communication. Analogously, the postsynaptic neurotransmitter receptor may be considered the quantum of fast chemical to electrical transduction. Our understanding of postsynaptic receptors began to develop about a hundred years ago with the demonstration that electrical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylcholine
Share to Action Potentials
Share to Models, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Myasthenia Gravis

Share to Protein Conformation

Share to Receptors, Cholinergic

Share to Structure-Activity Relationship

Share to Synaptic Transmission

Source

Open in PubMed Open full text

Identifiers

PMID: 22811427
DOI: 10.1152/physrev.00015.2011
PMCID: PMC3489064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

End-plate acetylcholine receptor: structure, mechanism, pharmacology, and disease.PMID 22811427Read ↗

Allosteric receptors: from electric organ to cognition.Semantic proximity Read ↗

Structure, diversity, and ionic permeability of neuronal and muscle acetylcholine receptors.Semantic proximity Read ↗

[The structure and function of nicotinic acetylcholine receptor].Semantic proximity Read ↗

Activation of ion channels by acetylcholine: two contrasting transduction pathways.Semantic proximity Read ↗

Therapeutic Potential of α7 Nicotinic Acetylcholine Receptors.Semantic proximity Read ↗

The Non-Neuronal Cholinergic System in Health and DiseaseSemantic proximity Read ↗

Nicotinic acetylcholine receptors: From basic science to therapeuticsSemantic proximity Read ↗

Structural basis of agonist selectivity for different nAChR subtypes: insights from crystal structures, mutation experiments and molecular simulations.Semantic proximity Read ↗

Nicotinic mechanisms in the autonomic control of organ systems.Semantic proximity Read ↗

Modal affinities of endplate acetylcholine receptors caused by loop C mutations.Semantic proximity Read ↗

New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome.Semantic proximity Read ↗

Ubiquitous expression of acetylcholine and its biological functions in life forms without nervous systemsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.