Article
The DNA repair gene PSO3 of Saccharomyces cerevisiae belongs to the RAD3 epistasis group.
Current genetics - 1 Jan 1992
Benfato M S, Brendel M, Henriques J A
Abstract excerpt
The mutant allele pso3-1 of Saccharomyces cerevisiae confers sensitivity to treatment with UV365nm (UVA) light-activated mono- and bi-functional psoralens. When pso3-1 is combined in double mutants with selected rad and pso mutant alleles and subjected to 8-MOP + UVA treatment, epistatic interaction with regard to survival is observed with pso1, pso2, and rad3. With the same treatment the combination of pso3-1...
Topics
- Alleles
- DNA Damage
- DNA Repair
- DNA, Fungal
- Epistasis, Genetic
- Furocoumarins
- Genes, Fungal
- Methoxsalen
- Mutation
- Saccharomyces cerevisiae
- Ultraviolet Rays
