Article
Low glutathione pools in the original pso3 mutant of Saccharomyces cerevisiae are responsible for its pleiotropic sensitivity phenotype.
Current genetics - 1 Jan 1998
Brendel M, Grey M, Maris A F, Hietkamp J, Fesus Z, Pich C T, Dafré A L, Schmidt M, Eckardt-Schupp F, Henriques J A
Abstract excerpt
The original pso3-1 mutant isolate of the yeast Saccharomyces cerevisiae exhibits a pleiotropic mutagen-sensitivity phenotype that includes sensitivity to UVA-activated 3-carbethoxypsoralen, to UVC-light, to mono- and bi-functional nitrogen mustard, to paraquat, and to cadmium; on the other hand,...
Topics
- Fungal Proteins
- Furocoumarins
- Gene Deletion
- Glutamate-Cysteine Ligase
- Glutathione
- Homeodomain Proteins
- Phenotype
- Photosensitizing Agents
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins