Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The von Hippel-Lindau Tumor Suppressor Stabilizes Novel Plant Homeodomain Protein Jade-1

1 Oct 2002

Abstract excerpt

The von Hippel-Lindau disease gene (VHL) is the causative gene for most adult renal cancers. However, the mechanism by which VHL protein functions as a renal tumor suppressor remains largely unknown. To identify low occupancy VHL protein partners with potential relevance to renal cancer, we screened a human kidney library against human VHL p30 using a yeast two-hybrid approach. Jade-1 (gene for Apoptosis and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Epigenetics and DNA Methylation
Share to Renal cell carcinoma treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12169691
DOI: 10.1074/jbc.m205040200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The von Hippel-Lindau Tumor Suppressor Stabilizes Novel Plant Homeodomain Protein Jade-1PMID 12169691Read ↗

Tumor suppressor von Hippel-Lindau (VHL) stabilization of Jade-1 protein occurs through plant homeodomains and is VHL mutation dependent.Semantic proximity Read ↗

The von Hippel-Lindau geneSemantic proximity Read ↗

Recent advances in etiology and treatment of von Hippel-Lindau Disease (VHLD).Semantic proximity Read ↗

PBRM1 and BAP1 as novel targets for renal cell carcinoma.Semantic proximity Read ↗

VHL, the story of a tumour suppressor gene.Semantic proximity Read ↗

Role of the<i>VHL</i>(von Hippel–Lindau) gene in renal cancer: a multifunctional tumour suppressorSemantic proximity Read ↗

New cancer targets emerging from studies of the Von Hippel-Lindau tumor suppressor protein.Semantic proximity Read ↗

[Von-Hippel-Lindau (VHL) protein function by initiation and progression of renal cancer].Semantic proximity Read ↗

ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancerSemantic proximity Read ↗

The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity.Semantic proximity Read ↗

Ubiquitin COOH-terminal hydrolase 1: a biomarker of renal cell carcinoma associated with enhanced tumor cell proliferation and migration.Semantic proximity Read ↗

The role of von Hippel-Lindau tumor suppressor protein and hypoxia in renal clear cell carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.