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Article

Ubiquitin COOH-terminal hydrolase 1: a biomarker of renal cell carcinoma associated with enhanced tumor cell proliferation and migration.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2007

Seliger Barbara, Fedorushchenko Alla, Brenner Walburgis, Ackermann Angelika, Atkins Derek, Hanash Samir, Lichtenfels Rudolf

Abstract excerpt

PURPOSE: Renal cell carcinoma (RCC) accounts for 2% to 3% of all malignancies. It represents one of the most radiation- and chemotherapy-resistant tumors and surgical resections are only effective in organ-defined disease. However, RCC is an immunogenic tumor with response rates to immunotherapies between 10% and 20% of the treated patients. Due to the currently inefficient therapies and the low 5-year survival...

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Source

Identifiers

PMID: 17200335
DOI: 10.1158/1078-0432.CCR-06-0824

Genes

UCHL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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