Article
Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning.
The Journal of biological chemistry - 18 Oct 2002
Weeber Edwin J, Beffert Uwe, Jones Chris, Christian Jill M, Forster Eckart, Sweatt J David, Herz Joachim
Abstract excerpt
Two apolipoprotein E (apoE) receptors, the very low density lipoprotein (VLDL) receptor and apoE receptor 2 (apoER2), are also receptors for Reelin, a signaling protein that regulates neuronal migration during brain development. In the adult brain, Reelin is expressed by GABA-ergic interneurons, suggesting a potential function as a modulator of neurotransmission. ApoE receptors have been indirectly implicated in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
