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Article

A rapid and easy method for multiple endocrine neoplasia type 1 mutation detection using conformation-sensitive gel electrophoresis.

Journal of human genetics - 1 Jan 2002

Arancha Cebrián, Ruíz-Llorente Sergio, Cascón Alberto, Osorio Ana, Martínez-Delgado Beatriz, Benítez Javier, Robledo Mercedes

Abstract excerpt

Until now, the study of the multiple endocrine neoplasia type 1 (MEN1) gene in patients suspected of having the disease was expensive and laborious due to the large size of the gene. We have optimized the conformation-sensitive gel electrophoresis (CSGE) technique to analyze by four rather simple multiplex PCR reactions, and a single electrophoresis run, the entire coding region of the MEN1 gene, plus the...

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Source

Identifiers

PMID: 12166655
DOI: 10.1007/s100380200022

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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