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Article

Salt consumption-dependent association of the GNB3 gene polymorphism with type 2 DM.

Biochemical and biophysical research communications - 26 Sept 2008

Daimon Makoto, Sato Hidenori, Sasaki Satoshi, Toriyama Sayumi, Emi Mitsuru, Muramatsu Masaaki, Hunt Steven C, Hopkins Paul N, Karasawa Shigeru, Wada Kiriko, Jimbu Yumi, Kameda Wataru, Susa Shinji, Oizumi Toshihide, Fukao Akira, Kubota Isao, Kawata Sumio, Kato Takeo

Abstract excerpt

The associations of the C825T polymorphism (rs5443) of the G-protein beta3 subunit (GNB3) gene and eight adjacent single nucleotide polymorphisms (SNPs) with diabetes were examined using a Japanese population (n (M/W): 2956 (1335/1621); age: 63.0+/-10.2 years). Fasting plasma glucose (FPG) levels were significantly associated with the C825T polymorphism and two flanking SNPs (rs2301339 and rs5446) (p=0.002,...

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Share to Blood Glucose
Share to Cross-Sectional Studies
Share to Diabetes Mellitus, Type 2
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Share to Heterotrimeric GTP-Binding Proteins
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Share to Sodium Chloride, Dietary

Source

Identifiers

PMID: 18656447
DOI: 10.1016/j.bbrc.2008.07.065

Genes

GNB3

Variants

rs5443

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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