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Article

The M184V mutation in reverse transcriptase can delay reversion of attenuated variants of simian immunodeficiency virus.

Journal of virology - 1 Sept 2002

Whitney James B, Oliveira Maureen, Detorio Mervi, Guan Yongjun, Wainberg Mark A

Abstract excerpt

We previously constructed a series of simian immunodeficiency virus (SIV) mutants containing deletions within a 97-nucleotide region of the SIVmac239 untranslated region or leader sequence. However, as is common with live attenuated viruses, several of the mutants exhibited a moderate propensity for reversion. Since the M184V mutation in human immunodeficiency virus type 1 reverse transcriptase is associated with...

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Identifiers

PMID: 12163615
DOI: 10.1128/jvi.76.17.8958-8962.2002
PMCID: PMC136968

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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