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Article

The detection of diverse aminoglycoside phosphotransferases within natural populations of actinomycetes.

Journal of industrial microbiology & biotechnology - 1 Aug 2002

Anderson A S, Clark D J, Gibbons P H, Sigmund J M

Abstract excerpt

The conserved nature of the genes that code for actinomycete secondary metabolite biosynthetic pathways suggests a common evolutionary ancestor and incidences of lateral gene transfer. Resistance genes associated with these biosynthetic pathways also display a high degree of similarity. Actinomycete aminoglycoside phosphotransferase antibiotic resistance enzymes (APH) are coded for by such genes and are therefore...

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PMID: 12161772
DOI: 10.1038/sj.jim.7000260

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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