Article
PCR detection of aminoglycoside resistance genes: a rapid molecular typing method for Acinetobacter baumannii.
Research in microbiology - 1 Jun 1999
Noppe-Leclercq I, Wallet F, Haentjens S, Courcol R, Simonet M
Abstract excerpt
Aminoglycoside resistance is common among strains of Acinetobacter baumannii responsible for nosocomial infections, and inactivation of these antibiotics by enzymatic modification is the main mechanism. Different types of aminoglycoside acetyltransferases (AAC), nucleotidyltransferases (ANT), and phosphotransferases (APH) are synthesized by clinical isolates, and several enzymes can be produced by a single...
Topics
- Acetyltransferases
- Acinetobacter
- Acinetobacter Infections
- Aminoglycosides
- Anti-Bacterial Agents
- Bacterial Typing Techniques
- Cross Infection
- DNA, Bacterial
- Drug Resistance, Microbial
- Electrophoresis, Gel, Pulsed-Field
- Gene Amplification
- Genes, Bacterial
- Genotype
- Humans
- Kanamycin Kinase
- Microbial Sensitivity Tests
- Nucleotidyltransferases
- Polymerase Chain Reaction