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Article

Regulation of synaptic plasticity and synaptic vesicle dynamics by the PDZ protein Scribble.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Aug 2002

Roche John P, Packard Mary C, Moeckel-Cole Stephanie, Budnik Vivian

Abstract excerpt

The Drosophila tumor suppressor Scribble (Scrib) is a PDZ-containing protein required for maintaining epithelial cell polarity. At the larval neuromuscular junction, Scrib colocalizes and indirectly interacts with another tumor suppressor and PDZ protein, Discs-Large (Dlg). Previous studies demonstrate that Dlg is critical for development of normal synapse structure and function, as well as for normal synaptic...

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Identifiers

PMID: 12151526
PMCID: PMC6758150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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