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Article

The neuronal protein Neurexin directly interacts with the Scribble-Pix complex to stimulate F-actin assembly for synaptic vesicle clustering.

The Journal of biological chemistry - 1 Sept 2017

Rui Menglong, Qian Jinjun, Liu Lijuan, Cai Yihan, Lv Huihui, Han Junhai, Jia Zhengping, Xie Wei

Abstract excerpt

Synaptic vesicles (SVs) form distinct pools at synaptic terminals, and this well-regulated separation is necessary for normal neurotransmission. However, how the SV cluster, in particular synaptic compartments, maintains normal neurotransmitter release remains a mystery. The presynaptic protein Neurexin (NRX) plays a significant role in synaptic architecture and function, and some evidence suggests that NRX is...

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Source

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Identifiers

PMID: 28710284
DOI: 10.1074/jbc.M117.794040
PMCID: PMC5582829

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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