Article
Fibrinogen and factor VII promoter polymorphisms in women with preeclampsia.
Obstetrics and gynecology - 1 Aug 2002
Laasanen Jaana, Hiltunen Mikko, Punnonen Kari, Mannermaa Arto, Heinonen Seppo
Abstract excerpt
OBJECTIVE: To determine whether genetic variability in the promoter regions of the genes encoding fibrinogen and factor VII contribute to individual differences in susceptibility to the development of preeclampsia. METHODS: The study involved 133 preeclamptic and 115 healthy control pregnant women who were genotyped for the G-455A polymorphism in the beta-fibrinogen gene promoter and for a decamer insertion or...
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