Article
Frequency of factor V, prothrombin and methylenetetrahydrofolate reductase gene variants in preeclampsia.
Gynecologic and obstetric investigation - 1 Jan 2002
D'Elia Angela V, Driul Lorenza, Giacomello Roberta, Colaone Roberta, Fabbro Dora, Di Leonardo Cristina, Florio Pasquale, Petraglia Felice, Marchesoni Diego, Damante Giuseppe
Abstract excerpt
BACKGROUND: The association between thrombophilic variants (Leiden mutation of the factor V gene, G20210A mutation of the prothrombin gene and C677T polymorphism of the methylenetetrahydrofolate reductase (MTHFR) gene) with preeclampsia was investigated in a north-eastern Italian population. METHODS: Fifty-eight preeclamptic (PE) women and 74 normal pregnancies were evaluated. Genotypes were determined by...
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