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Article

Interleukin-1 in the genesis and progression of and risk for development of neuronal degeneration in Alzheimer's disease.

Journal of leukocyte biology - 1 Aug 2002

Griffin W Sue T, Mrak Robert E

Abstract excerpt

Interleukin-1 (IL-1), a key molecule in systemic immune responses in health and disease, has analogous roles in the brain where it may contribute to neuronal degeneration. Numerous findings suggest that this is the case. For example, IL-1 overexpression in the brain of Alzheimer patients relates directly to the development and progression of the cardinal neuropathological changes of Alzheimer's disease, i.e., the...

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Identifiers

PMID: 12149413
PMCID: PMC3835694

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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