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Article

Association of IL-1 RN*2 allele and methionine synthase 2756 AA genotype with dementia severity of sporadic Alzheimer's disease.

Journal of neurology, neurosurgery, and psychiatry - 1 Jul 2004

Bosco P, Guéant-Rodríguez R-M, Anello G, Romano A, Namour B, Spada R S, Caraci F, Tringali G, Ferri R, Guéant J-L

Abstract excerpt

BACKGROUND: Genetic polymorphisms of APO-E, homocysteine, and the IL-1 gene cluster (IL-1A, IL-1B, receptor antagonist IL-1RN) are associated with sporadic Alzheimer's disease and may involve interdependent pathways of neuronal toxicity. OBJECTIVE: To determine whether these polymorphisms and the...

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Source

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Identifiers

PMID: 15201366
DOI: 10.1136/jnnp.2003.025866
PMCID: PMC1739095

Genes

MTR
MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15201366-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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