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Article

Interleukin-1 and the immunogenetics of Alzheimer disease.

Journal of neuropathology and experimental neurology - 1 Jun 2000

Mrak R E, Griffin W S

Abstract excerpt

Established genetic causes of familial Alzheimer disease (AD) involve genes for beta-amyloid precursor protein (betaAPP), presenilin-1, and presenilin-2. For the more common sporadic forms of AD, increased risk has been associated with a number of genes; the most important of which is the epsilon4 allele of apolipoprotein E. Two recent studies, one clinical and one using postmortem material, now show increased...

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Identifiers

PMID: 10850859
DOI: 10.1093/jnen/59.6.471
PMCID: PMC3833594

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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