Article
The superantigen gene ypm is located in an unstable chromosomal locus of Yersinia pseudotuberculosis.
Journal of bacteriology - 1 Aug 2002
Carnoy Christophe, Floquet Stephanie, Marceau Michael, Sebbane Florent, Haentjens-Herwegh Stephanie, Devalckenaere Annie, Simonet Michel
Abstract excerpt
Yersinia pseudotuberculosis produces YPM (Y. pseudotuberculosis-derived mitogen), a superantigenic toxin that exacerbates the virulence of the bacterium in vivo. To date, three alleles of the superantigen gene (ypmA, ypmB, and ypmC) have been described. These genes are not found in all Y. pseudotuberculosis strains and have a low GC content, suggesting their location on mobile genetic elements. To elucidate this...
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