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Article

Therapeutic efficacy of sulfadoxine-pyrimethamine and the prevalence of molecular markers of resistance in under 5-year olds in Brazzaville, Congo.

Tropical medicine & international health : TM & IH - 1 Oct 2007

Ndounga Mathieu, Tahar Rachida, Basco Leonardo K, Casimiro Prisca N, Malonga David A, Ntoumi Francine

Abstract excerpt

OBJECTIVE: To test the efficacy of sulfadoxine-pyremethamine (SP) monotherapy and establish the prevalence of mutations in dhfr and dhps in Brazzaville, Congo. METHOD: We recruited 97 patients aged 6-59 months with uncomplicated malaria who attended Tenrikyo public health centre. Eighty-three were followed until day 28. SP efficacy was determined by the WHO 28-day test and analysis of mutations in the Plasmodium...

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Identifiers

PMID: 17956498
DOI: 10.1111/j.1365-3156.2007.01904.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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