Article
Influence of nitric oxide synthase gene polymorphisms on the risk of cardiovascular events in rheumatoid arthritis.
Clinical and experimental rheumatology - 1 Jan 2000
Gonzalez-Gay M A, Llorca J, Palomino-Morales R, Gomez-Acebo I, Gonzalez-Juanatey C, Martin J
Abstract excerpt
OBJECTIVE: Complex interactions between environmental and genetic determinants in both the host immune system and the vasculature may operate modifying the vascular risk in rheumatoid arthritis (RA). An increased incidence of cardiovascular (CV) events in RA patients carrying HLA-DRB1 shared epitope alleles, in particular HLA-DRB1*0404, has recently been found. In the present study we have assessed the potential...
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