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Article

Antibody-based approach to high-volume genotyping for MIC-1 polymorphism.

BioTechniques - 1 Jul 2002

Brown D A, Bauskin A R, Fairlie W D, Smith M D, Liu T, Xu N, Breit S N

Abstract excerpt

Macrophage inhibitory cytokine-1 (MIC-1) is a divergent member of the TGF-beta superfamily. There are at least two known alleles of MIC-1 that are due to a G-->C point substitution at position 6 of the mature protein, which alters a histidine to an aspartic acid (MIC-1 H and MIC-1 D). We have determined the phenotype of MIC-1 circulating in serum by exploiting the differences in the affinity of the two monoclonal...

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Share to Cytokines
Share to DNA Mutational Analysis
Share to Enzyme-Linked Immunosorbent Assay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

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Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 12139236
DOI: 10.2144/02331rr03

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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