Article
'Hbe minus' mutants of hepatitis B virus. Molecular characterization and its relation to viral genotypes.
Virus research - 1 Jul 2002
López J L, Mbayed V A, Telenta P F S, González J E, Campos Rodolfo Héctor
Abstract excerpt
The precore-core and S genes of HBV were directly sequenced from serum samples of 42 patients with chronic hepatitis B (16 hepatitis Be antigen [HBeAg]+and 26 anti-HBe+). Viral genotype A was identified in 12 cases, genotype D in 11 and genotype F in 19 cases. Precore mutations, mainly M1 (G1896A, stop at codon 28) were similarly found among viral genotypes A and D: seven cases (58%) and six cases (55%),...
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