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Hepatitis B virus genotype distribution and genotype-specific BCP/preCore substitutions in acute and chronic infections in Argentina.

PloS one - 1 Jan 2015

González López Ledesma María Mora, Mojsiejczuk Laura Noelia, Rodrigo Belén, Sevic Ina, Mammana Lilia, Galdame Omar, Gadano Adrian, Fainboim Hugo, Campos Rodolfo, Flichman Diego

Abstract excerpt

AIM: In order to assess Hepatitis B Virus genotype (g) and subgenotype (sg) implications in the course of infection, 234 HBsAg positive patients in different infection stages were characterized (66 acute infections, 63 HBeAg positive chronic infections and 105 anti-HBe positive chronic infections). RESULTS: Overall, sgA2 (17.9%), gD (20.9%), sgF1b (34.2%) and sgF4 (19.7%) were the most prevalent. Subgenotype F1b...

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Identifiers

PMID: 25822666
DOI: 10.1371/journal.pone.0121436
PMCID: PMC4378996

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