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Article

The precore mutation is associated with severity of liver damage in Brazilian patients with chronic hepatitis B.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jan 2005

Rezende Rosamar E F, Fonseca Benedito A L, Ramalho Leandra N Z, Zucoloto Sérgio, Pinho João Renato R, Bertolini Dennis A, Martinelli Ana L C

Abstract excerpt

BACKGROUND: The clinical relevance of the G1896A precore mutation in chronic hepatitis B is still poorly understood. OBJECTIVES: To assess the frequency of G1896A precore mutation in Brazilian patients with chronic hepatitis B, as well as its relation to the viral genotype, serum HBV-DNA levels and liver damage. STUDY DESIGN: Fifty chronic hepatitis B patients (29 HBeAg-negative and 21 HBeAg-positive) were...

Topics

Brazil
DNA, Viral
Female
Hepatitis B virus
Hepatitis B, Chronic
Humans
Liver
Male
Mutation
Severity of Illness Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Viral Core Proteins

Viremia

Source

Identifiers

PMID: 15572007
DOI: 10.1016/j.jcv.2004.08.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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The precore mutation is associated with severity of liver damage in Brazilian patients with chronic hepatitis B.PMID 15572007Read ↗

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Correlation between hepatitis B genotypes, 1896 precore mutation, virus loads and liver dysfunction in an Indian population.Semantic proximity Read ↗

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