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Article

TNFalpha-308A associated with shorter intervals of Plasmodium falciparum reinfections.

Tissue antigens - 1 Apr 2002

Meyer C G, May J, Luty A J, Lell B, Kremsner P G

Abstract excerpt

A mutation at position -308 of the tumor necrosis factor alpha (TNF-308A) gene promoter has previously been associated with particular manifestations of infectious and non-infectious diseases. In a longitudinal study on malariological parameters in Gabon, TNF promoter variants of 98 children initially presenting with severe Plasmodium falciparum malaria, followed by a total of 504 reinfection events within 52...

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Source

Identifiers

PMID: 12135427
DOI: 10.1034/j.1399-0039.2002.590406.x

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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TNFalpha-308A associated with shorter intervals of Plasmodium falciparum reinfections.PMID 12135427Read ↗

TNF-α promoter variant (G-308A) is associated with susceptibility to P. falciparum infection and severe malaria: a meta-analysis and trial sequential analysis.Semantic proximity Read ↗

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Combined promoter haplotypes of the IL10R genes are associated with protection against severe malaria in Gabonese children.Semantic proximity Read ↗

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Tumor necrosis factor-alpha promoter variant 2 (TNF2) is associated with pre-term delivery, infant mortality, and malaria morbidity in western Kenya: Asembo Bay Cohort Project IX.Semantic proximity Read ↗

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Association of a functional TNF variant with Plasmodium falciparum parasitaemia in a congolese population.Semantic proximity Read ↗

Alleles -308A and -1031C in the TNF-alpha gene promoter do not increase the risk but associated with circulating levels of TNF-alpha and clinical features of vivax malaria in Indian patients.Semantic proximity Read ↗

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