Article

Molecular Detection of the -308 G/A Polymorphism in the Tumor Necrosis Factor Alpha (TNFα) Gene Promoter and Its Relationship with the Development of Severe Dengue in Patients from Urabá Subregion, Antioquia-Colombia

2026-08-28

Abstract excerpt

<h4>Background: </h4> dengue fever is a viral infection caused by the Dengue Virus (DENV), a positive-sense RNA virus belonging to Flaviviridae family. The virus is transmitted to humans through the bite of the Aedes aegypti mosquito. Worldwide, between 100 and 400 million cases are reported annually. The infection in humans can cause three clinical forms which are related to severity: dengue without warnings sign...

Identifiers and source

Literature Corpus work: c4a2ea21-206f-59e3-81ad-04be604a5d1a
DOI: 10.20944/preprints202608.2135.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Click a neighbor to travelStep 1 · 12 closest

Molecular Detection of the -308 G/A Polymorphism in the Tumor Necrosis Factor Alpha (TNFα) Gene Promoter and Its Relationship with the Development of Severe Dengue in Patients from Urabá Subregion, Antioquia-ColombiaDOI 10.20944/preprints202608.2135.v1Read

Association of single nucleotide polymorphisms in TNF-α (-308G/A and -238G/A) to dengue: Case-control and meta-analysis study.Semantic proximity Read

Tumour necrosis factor gene polymorphism in dengue infection: association with risk of bleeding.Semantic proximity Read

Meta-Analysis of the Relationship between TNF-α (-308G/A) and IL-10 (-819C/T) Gene Polymorphisms and Susceptibility to Dengue.Semantic proximity Read

Associations of tumor necrosis factor-α-308 polymorphism with dengue infection: A systematic review and meta-analysis.Semantic proximity Read

TNF-alpha-308A allele, a possible severity risk factor of hemorrhagic manifestation in dengue fever patients.Semantic proximity Read

High producing tumor necrosis factor alpha gene alleles in protection against severe manifestations of dengue.Semantic proximity Read

The Genetic Variant TNFA (rs361525) Is Associated with Increased Susceptibility to Developing Dengue Symptoms.Semantic proximity Read

Tumor necrosis factor alpha promoter polymorphisms in Mexican patients with dengue fever.Semantic proximity Read

Association of TNF-α-308G/A Gene Polymorphism with Coronavirus Disease-19 SeveritySemantic proximity Read

Single nucleotide polymorphisms in candidate genes and dengue severity in children: a case-control, functional and meta-analysis study.Semantic proximity Read

Genetic Polymorphisms of Tumor Necrosis Factor Alpha and Susceptibility to Dengue Virus Infection in a Mexican Population.Semantic proximity Read

Association of Single-Nucleotide Polymorphisms in Immune-Related Genes with Development of Dengue Hemorrhagic Fever in a Mexican Population.Semantic proximity Read