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Article

Association of a functional TNF variant with Plasmodium falciparum parasitaemia in a congolese population.

Genes and immunity - 1 Sept 2017

Nguyen T N, Baaklini S, Koukouikila-Koussounda F, Ndounga M, Torres M, Pradel L, Ntoumi F, Rihet P

Abstract excerpt

Several studies have provided evidence of both helpful and harmful effects of TNF on the outcome of Plasmodium falciparum malaria infection. Several TNF polymorphisms that are located within non-coding regions have been associated with parasitaemia, mild malaria or severe malaria. We investigated the association of TNF1304 (rs3093664), TNF-308 (rs1800629), TNF-238 (rs361525) and TNF-244 (rs673) with mild malaria...

Topics

Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Child, Preschool

Congo

Female

Humans

Infant

Malaria

Male

Parasitemia

Plasmodium falciparum

Polymorphism, Single Nucleotide

Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 28703132
DOI: 10.1038/gene.2017.13

Genes

TNF

Provenance

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