Article
A polymorphism in lipoprotein lipase affects the severity of Alzheimer's disease pathophysiology.
The European journal of neuroscience - 1 Sept 2006
Blain Jean-François, Aumont Nicole, Théroux Louise, Dea Doris, Poirier Judes
Abstract excerpt
Emerging evidences indicate a role for lipoprotein lipase (LPL) in degenerative states. Genetic variations in the LPL gene were previously associated to lipid imbalance and coronary artery disease (CAD) risk and severity, a condition that shares pathological features with common Alzheimer's disease (AD). To evaluate whether these genetic variations associate with the risk and pathophysiology of common AD,...
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