Article
Roles for lipoprotein lipase in Alzheimer's disease: an association study.
Microscopy research and technique - 15 Aug 2000
Baum L, Wiebusch H, Pang C P
Abstract excerpt
Lipoprotein lipase (LPL) assists lipid transport by transferring lipids between lipoprotein particles and cells. LPL binds apolipoprotein E (apoE) lipoprotein particles and a major apoE receptor, low density lipoprotein receptor related protein (LRP). Because apoE and LRP polymorphisms alter Alzheimer's disease (AD) risk, and LPL itself is found in AD amyloid plaques, we examined whether LPL variants also affect...
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