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Article

Isolation of differentially expressed genes from wild-type and Twist mutant mouse limb buds.

Genesis (New York, N.Y. : 2000) - 1 Jul 2002

Loebel David A F, O'Rourke Meredith P, Steiner Kirsten A, Banyer Joanne, Tam Patrick P L

Abstract excerpt

In the mouse, Twist is required for normal limb and craniofacial development. We show that the aristaless-like transcription factors, Alx3 and Alx4 are downregulated in the Twist(-/-) mutant and may be potential targets of Twist. By suppression subtractive hybridization we isolated 31 and 18 unique clones representing mRNAs that are putatively downregulated and upregulated respectively in Twist(-/-) forelimb...

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Source

Identifiers

PMID: 12124942
DOI: 10.1002/gene.10091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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