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Article

Cloning of the human twist gene: Its expression is retained in adult mesodermally-derived tissues

1 Mar 1997

Abstract excerpt

We have previously reported on the isolation of several differentially expressed genes derived from young and senescent non growing WI-38 human fetal lung-derived fibroblasts. A 0.8-kb cDNA clone, isolate EPC-A2 (early population doubling cDNA-A2), encodes the 3' end of the human homolog of the Twist protein. Twist genes encode basic helix-loop-helix DNA-binding transcription factors that play crucial roles in...

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PMID: 9073070
DOI: 10.1016/s0378-1119(96)00727-5

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