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Article

Molecular genetic analysis of malignant melanomas for aberrations of the WNT signaling pathway genes CTNNB1, APC, ICAT and BTRC.

International journal of cancer - 10 Aug 2002

Reifenberger Julia, Knobbe Christiane B, Wolter Marietta, Blaschke Britta, Schulte Klaus W, Pietsch Torsten, Ruzicka Thomas, Reifenberger Guido

Abstract excerpt

Aberrant activation of the Wnt signaling pathway has been reported in different human tumor types, including malignant melanomas. We investigated 37 malignant melanomas (15 primary tumors and 22 metastases) for alterations of 4 genes encoding members of this pathway, i.e., CTNNB1 (beta-catenin ge...

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Source

Identifiers

PMID: 12124804
DOI: 10.1002/ijc.10512

Genes

APC
CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12124804-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Molecular genetic analysis of malignant melanomas for aberrations of the WNT signaling pathway genes CTNNB1, APC, ICAT and BTRC.PMID 12124804Read ↗

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